top of page

研究業績

発表論文

researchmap130.gif

  1. Shogo Hamada*, Keiji Murayama, Yusuke Takezawa, Ryojun Toyoda, Akinori Kuzuya*, "Omega Nucleic Acids (ΩNA), Ultimate Nucleic Acids for Future Technology", Molecules, 2026, 31, 523. 📖

  2. Yusuke Takezawa* and Mitsuhiko Shionoya*, “Rational Design Strategies for Stimuli-Responsive DNAzymes Using Modified and Artificial Nucleotides”, Chem. Eur. J., 2026, in press. 📖

  3. Yusuke Takezawa* and Mitsuhiko Shionoya*, “Enzymatic synthesis of ligand-bearing oligonucleotides for the development of metal-responsive DNA materials”, Org. Biomol. Chem., 2024, 22, 7259–7270.📖

  4. Yusuke Takezawa*, “Rational design of metal-responsive functional DNA supramolecules”, J. Incl. Phenom. Macrocycl. Chem., 2024, 104, 349–369.📖

  5. Yusuke Takezawa,* Naofumi Kudo, Nobuyuki Fuse, and Mitsuhiko Shionoya*, “DNA three-way junction structures with amino acid side chains prepared via post-synthetic amide condensation”, Nucleosides Nucleotides Nucleic Acids, 2024, 43, 951–964.📖

  6. Yusuke Takezawa,* Hanci Zhang, Keita Mori, Lingyun Hu, and Mitsuhiko Shionoya*, “Ligase-mediated Synthesis of Cu(II)-responsive Allosteric DNAzyme with Bifacial 5-Carboxyuracil Nucleobases”, Chem. Sci., 2024, 15, 2365–2370. (Inside back cover)📖

  7. Yusuke Takezawa,* Lingyun Hu, Takahiro Nakama, and Mitsuhiko Shionoya*, “Metal-dependent activity control of a compact-sized 8-17 DNAzyme based on metal-mediated unnatural base pairing”, Chem. Commun., 2024, 60, 288–291. (Back cover)📖

  8. Yusuke Takezawa,* Keita Mori, Wei-En Huang, Kotaro Nishiyama, Tong Xing, Takahiro Nakama, and Mitsuhiko Shionoya*, “Metal-mediated DNA Strand Displacement and Molecular Device Operations Based on Base-pair Switching of 5-Hydroxyuracil Nucleobases”, Nat. Commun., 2023, 14, 4759. 📖

  9. Yusuke Takezawa,* Daisuke Kanemaru, Naofumi Kudo, and Mitsuhiko Shionoya*, “Phenanthroline-modified DNA Three-way Junction Structures Stabilized by Interstrand 3:1 Metal Complexation”, Dalton Trans., 2023, 52, 11025–11029. (Front cover)📖

  10. Keita Mori, Yusuke Takezawa,* and Mitsuhiko Shionoya*, “Metal-dependent base pairing of bifacial iminodiacetic acid-modified uracil bases for switching DNA hybridization partner”, Chem. Sci., 2023, 14, 1082–1088. https://doi.org/10.1039/d2sc06534g. (Back cover)📖

  11. Silpa Chandran Rajasree, Yusuke Takezawa,* and Mitsuhiko Shionoya*. “Cu(II)-mediated stabilisation of DNA duplexes bearing consecutive ethenoadenine lesions and its application to a metal-responsive DNAzyme”. Chem. Commun., 2023, 59, 1006–1009. (Front cover)📖

  12. Lingyun Hu, Yusuke Takezawa,* and Mitsuhiko Shionoya*, “Cu(II)-mediated DNA base pairing of a triazole-4-carboxylate nucleoside prepared by click chemistry”, Chem. Commun., 2023, 59, 892–895.📖

  13. Lingyun Hu, Yusuke Takezawa,* and Mitsuhiko Shionoya*, “Metal-mediated DNA base pairing of easily prepared 2-oxo-imidazole-4-carboxylate nucleotides”, Chem. Sci., 2022, 13, 3977–3983. (Back cover)📖

  14. Yusuke Takezawa,* Shiori Sakakibara, and Mitsuhiko Shionoya*, “Bipyridine-modified DNA Three-way Junctions with Amide-linkers: Metal-dependent Structure Induction and Self-sorting”, Chem. Eur. J., 2021, 27, 16626–16633. (Front cover)📖

  15. Kotaro Nishiyama, Keita Mori, Yusuke Takezawa, and Mitsuhiko Shionoya*, “Metal-responsive Reversible Binding of Triplex-forming Oligonucleotides with 5-Hydroxyuracil Nucleobases”, Chem. Commun., 2021, 57, 2487–2490. (Back cover)📖

  16. Takahiro Nakama, Yusuke Takezawa, and Mitsuhiko Shionoya*, “Site-Specific Polymerase Incorporation of Consecutive Ligand-Containing Nucleotides for Multiple Metal-Mediated Base Pairing”, Chem. Commun., 2021, 57, 1392–1395.📖

  17. Yusuke Takezawa, Akira Suzuki, Manabu Nakaya, Kotaro Nishiyama, and Mitsuhiko Shionoya*, “Metal-Dependent DNA Base Pairing of 5-Carboxyuracil with Itself and All Four Canonical Nucleobases”, J. Am. Chem. Soc., 2020, 142, 21640–21644.📖

  18. Yusuke Takezawa, Lingyun Hu, Takahiro Nakama, and Mitsuhiko Shionoya*, “Sharp Switching of DNAzyme Activity through the Formation of Cu(II)-mediated Carboxyimidazole Base Pair”, Angew. Chem., Int. Ed., 2020, 59, 21488–21492.📖

  19. Takahiro Nakama, Yusuke Takezawa, Daisuke Sasaki, and Mitsuhiko Shionoya*, “Allosteric Regulation of DNAzyme Activities through Intrastrand Transformation Induced by Cu(II)-Mediated Artificial Base Pairing”, J. Am. Chem. Soc., 2020, 142, 10153–10162.📖

  20. Yusuke Takezawa and Mitsuhiko Shionoya*, “Supramolecular DNA Three-way Junction Motifs with a Bridging Metal Center”, Front. Chem., 2020, 7, 925.📖

  21. Yusuke Takezawa, Takahiro Nakama, and Mitsuhiko Shionoya*, “Enzymatic Synthesis of Cu(II)-Responsive Deoxyribozymes through Polymerase Incorporation of Artificial Ligand-Type Nucleotides”, J. Am. Chem. Soc., 2019, 141, 19342–19350.📖

  22. Yusuke Takezawa, Jens Müller,* and Mitsuhiko Shionoya*, “Artificial DNA Base Pairing Mediated by Diverse Metal Ions”, Chem. Lett., 2017, 46, 622–633.📖

  23. Yusuke Takezawa, Teruki Kobayashi, and Mitsuhiko Shionoya*, “The Effects of Magnesium Ions on the Enzymatic Synthesis of Ligand-Bearing Artificial DNA by Template-Independent Polymerase”. Int. J. Mol. Sci., 2016, 17, 906.📖

  24. Kotaro Nishiyama, Yusuke Takezawa, and Mitsuhiko Shionoya*, “pH-Dependence of the Thermal Stability of Metallo-DNA Duplexes Containing Ligand-Type 5-Hydroxyuracil Nucleobases”, Inorg. Chim. Acta, 2016, 452, 176–180.📖

  25. Yusuke Takezawa, Shuhei Yoneda, Jean-Louis H. A. Duprey, Takahiro Nakama, and Mitsuhiko Shionoya*, “Metal-Responsive Structural Transformation between Artificial DNA Duplexes and Three-Way Junctions”, Chem. Sci., 2016, 7, 3006–3010. (Inside back cover)📖

  26. Teruki Kobayashi, Yusuke Takezawa, Akira Sakamoto, and Mitsuhiko Shionoya*, “Enzymatic Synthesis of Ligand-bearing DNAs for Metal-Mediated Base Pairing utilising a Template-Independent Polymerase”, Chem. Commun., 2016, 52, 3762–3765. (Back cover)📖

  27. Yusuke Takezawa, Kotaro Nishiyama, Tsukasa Mashima, Masato Katahira, and Mitsuhiko Shionoya*, “Bifacial Base-Pairing Behaviors of 5-Hydroxyuracil DNA Bases through Hydrogen Bonding and Metal Coordination”, Chem. Eur. J., 2015, 21, 14713–14716.📖

  28. Jean-Louis H. A. Duprey, Yusuke Takezawa, and Mitsuhiko Shionoya*, “Metal-Locked DNA Three-Way Junction”, Angew. Chem., Int. Ed., 2013, 52, 1212–1216.📖

  29. Yusuke Takezawa and Mitsuhiko Shionoya*, “Metal-Mediated DNA Base Pairing: Alternatives to Hydrogen-Bonded Watson–Crick Base Pairs”, Acc. Chem. Res., 2012, 45, 2066–2076.📖

  30. Rie Yamashige, Michiko Kimoto, Yusuke Takezawa, Akira Sato, Tsuneo Mitsui, Shigeyuki Yokoyama, and Ichiro Hirao*, “Highly Specific Unnatural Base Pair Systems as a Third Base Pair for PCR Amplification”, Nucleic Acids Res., 2012, 40, 2793–2806.📖

  31. Song Liu, Guido H. Clever, Yusuke Takezawa, Motoo Kaneko, Kentaro Tanaka, Xuefeng Guo,* and Mitsuhiko Shionoya*, “Direct Conductance Measurement of Individual Metallo-DNA Duplexes within Single-Molecule Break Junctions”, Angew. Chem., Int. Ed., 2011, 50, 8886–8890.  (Inside cover) 📖

  32. Yusuke Takezawa, Philipp Böckmann, Naoki Sugi, Ziyue Wang, Satoshi Abe, Tatsuya Murakami, Tatsuo Hikage, Gerhard Erker, Yoshihito Watanabe,* Susumu Kitagawa, and Takafumi Ueno*, “Incorporation of Organometallic Ru Complexes into Apo-Ferritin Cage”, Dalton Trans., 2011, 40, 2190–2195. 📖

  33. Ziyue Wang, Yusuke Takezawa, Hiroki Aoyagi, Satoshi Abe, Tatsuo Hikage, Yoshihito Watanabe, Susumu Kitagawa, and Takafumi Ueno*, “Definite Coordination Arrangement of Organometallic Palladium Complexes Accumulated on the Designed Interior Surface of Apo-Ferritin”, Chem. Commun., 2011, 47, 170–172.📖

  34. Yusuke Takezawa, Wakana Maeda, Kentaro Tanaka, and Mitsuhiko Shionoya*, “Discrete Self-Assembly of Iron(III) Ions inside Triple-Stranded Artificial DNA”, Angew. Chem., Int. Ed., 2009, 48, 1081­–1084.📖

  35. Satoshi Abe, Jochen Niemeyer, Mizue Abe, Yusuke Takezawa, Takafumi Ueno,* Tatsuo Hikage, Gerhard Erker, and Yoshihito Watanabe*, “Control of the Coordination Structure of Organometallic Palladium Complexes in an apo-Ferritin Cage”, J. Am. Chem. Soc., 2008, 130, 10512–10514.📖

  36. Yusuke Takezawa, Kentaro Tanaka, Maiko Yori, Shohei Tashiro, Motoo Shiro, and Mitsuhiko Shionoya*, “Soft Metal-Mediated Base Pairing with Novel Synthetic Nucleosides Possessing an O,S-Donor Ligand”, J. Org. Chem., 2008, 73, 6092–6098.📖

  37. Kentaro Tanaka, Guido H. Clever, Yusuke Takezawa, Yasuyuki Yamada, Corinna Kaul, Mitsuhiko Shionoya,* and Thomas Carell*, “Programmable Self-Assembly of Metal Ions inside Artificial DNA Duplexes”, Nature Nanotechnol., 2006, 1, 190–194.📖

bottom of page